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The synergistic inhibitory effect of combining therapies targeting EGFR and mitochondria in sarcomas

Our group previously demonstrated that sarcoma cell lines were insensitive to epidermal growth factor receptor (EGFR) inhibitor gefitinib monotherapy. PENAO, an anti-tumour metabolic compound created in our laboratory, is currently in clinical trials. Considering the positive regulation of tumour en...

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Foilsithe in:Oncotarget
Main Authors: Wang, Xiaochun, Yeo, Reichelle X., Hogg, Philip J., Goldstein, David, Crowe, Philip, Dilda, Pierre J., Yang, Jia-Lin
Formáid: Artigo
Teanga:Inglês
Foilsithe: Impact Journals LLC 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6967775/
https://ncbi.nlm.nih.gov/pubmed/32002123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27416
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