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The synergistic inhibitory effect of combining therapies targeting EGFR and mitochondria in sarcomas

Our group previously demonstrated that sarcoma cell lines were insensitive to epidermal growth factor receptor (EGFR) inhibitor gefitinib monotherapy. PENAO, an anti-tumour metabolic compound created in our laboratory, is currently in clinical trials. Considering the positive regulation of tumour en...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Wang, Xiaochun, Yeo, Reichelle X., Hogg, Philip J., Goldstein, David, Crowe, Philip, Dilda, Pierre J., Yang, Jia-Lin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6967775/
https://ncbi.nlm.nih.gov/pubmed/32002123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27416
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