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The synergistic inhibitory effect of combining therapies targeting EGFR and mitochondria in sarcomas

Our group previously demonstrated that sarcoma cell lines were insensitive to epidermal growth factor receptor (EGFR) inhibitor gefitinib monotherapy. PENAO, an anti-tumour metabolic compound created in our laboratory, is currently in clinical trials. Considering the positive regulation of tumour en...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wang, Xiaochun, Yeo, Reichelle X., Hogg, Philip J., Goldstein, David, Crowe, Philip, Dilda, Pierre J., Yang, Jia-Lin
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6967775/
https://ncbi.nlm.nih.gov/pubmed/32002123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27416
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