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Targeting STAT3 and STAT5 in Tumor-Associated Immune Cells to Improve Immunotherapy
Oncogene-induced STAT3-activation is central to tumor progression by promoting cancer cell expression of pro-angiogenic and immunosuppressive factors. STAT3 is also activated in infiltrating immune cells including tumor-associated macrophages (TAM) amplifying immune suppression. Consequently, STAT3...
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| Publicado no: | Cancers (Basel) |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6966642/ https://ncbi.nlm.nih.gov/pubmed/31766350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11121832 |
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