Chargement en cours...
Unleashing antitumor T-cell activation without ensuing autoimmunity: the case for A20-deletion in adoptive CD8(+) T-cell therapy
Mechanisms controlling immune reactivity prevent excessive inflammation and autoimmunity, but generally dampen antitumor activity. We recently showed that adoptively transferred antitumor CD8(+) T cells harboring a deletion of A20/Tnfaip3, a molecule controlling NF-κB activation, possessed heightene...
Enregistré dans:
| Publié dans: | Oncoimmunology |
|---|---|
| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Taylor & Francis
2014
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4292241/ https://ncbi.nlm.nih.gov/pubmed/25941582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.958951 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|