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Control of CD8 T cell proliferation and terminal differentiation by active STAT5 and CDKN2A/CDKN2B
CD8 T cells used in adoptive immunotherapy may be manipulated to optimize their effector functions, tissue-migratory properties and long-term replicative potential. We reported that antigen-stimulated CD8 T cells transduced to express an active form of the transcription factor signal transducer and...
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| Publicat a: | Immunology |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley & Sons, Ltd
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4515134/ https://ncbi.nlm.nih.gov/pubmed/25882552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12471 |
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