Control of CD8 T cell proliferation and terminal differentiation by active STAT5 and CDKN2A/CDKN2B

CD8 T cells used in adoptive immunotherapy may be manipulated to optimize their effector functions, tissue-migratory properties and long-term replicative potential. We reported that antigen-stimulated CD8 T cells transduced to express an active form of the transcription factor signal transducer and...

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Bibliographic Details
Published in:Immunology
Main Authors: Grange, Magali, Giordano, Marilyn, Mas, Amandine, Roncagalli, Romain, Firaguay, Guylène, Nunes, Jacques A, Ghysdael, Jacques, Schmitt-Verhulst, Anne-Marie, Auphan-Anezin, Nathalie
Format: Artigo
Language:Inglês
Published: John Wiley & Sons, Ltd 2015
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4515134/
https://ncbi.nlm.nih.gov/pubmed/25882552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12471
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