Disrupted Lymph Node and Splenic Stroma in Mice with Induced Inflammatory Melanomas Is Associated with Impaired Recruitment of T and Dendritic Cells

Migration of dendritic cells (DC) from the tumor environment to the T cell cortex in tumor-draining lymph nodes (TDLN) is essential for priming naïve T lymphocytes (TL) to tumor antigen (Ag). We used a mouse model of induced melanoma in which similar oncogenic events generate two phenotypically dist...

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Detalhes bibliográficos
Main Authors: Soudja, Saïdi M., Henri, Sandrine, Mello, Marielle, Chasson, Lionel, Mas, Amandine, Wehbe, Maria, Auphan-Anezin, Nathalie, Leserman, Lee, Van den Eynde, Benoît, Schmitt-Verhulst, Anne-Marie
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141075/
https://ncbi.nlm.nih.gov/pubmed/21811640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022639
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