Distinct patterns of cytolytic T‐cell activation by different tumour cells revealed by Ca(2+) signalling and granule mobilization

Cancer‐germline genes in both humans and mice have been shown to encode antigens susceptible to targeting by cytotoxic CD8 T effector cells (CTL). We analysed the ability of CTL to kill different tumour cell lines expressing the same cancer‐germline gene P1A (Trap1a). We previously demonstrated that...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Frick, Melissa, Mouchacca, Pierre, Verdeil, Grégory, Hamon, Yannick, Billaudeau, Cyrille, Buferne, Michel, Fallet, Mathieu, Auphan‐Anezin, Nathalie, Schmitt‐Verhulst, Anne‐Marie, Boyer, Claude
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214755/
https://ncbi.nlm.nih.gov/pubmed/27716898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12679
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