Grp78 Loss in Epithelial Progenitors Reveals an Age-linked Role for Endoplasmic Reticulum Stress in Pulmonary Fibrosis

Rationale: Alveolar epithelial cell (AEC) injury and dysregulated repair are implicated in the pathogenesis of pulmonary fibrosis. Endoplasmic reticulum (ER) stress in AEC has been observed in idiopathic pulmonary fibrosis (IPF), a disease of aging. Objectives: To investigate a causal role for ER st...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Am J Respir Crit Care Med
Hauptverfasser: Borok, Zea, Horie, Masafumi, Flodby, Per, Wang, Hongjun, Liu, Yixin, Ganesh, Sivagini, Firth, Amy L., Minoo, Parviz, Li, Changgong, Beers, Michael F., Lee, Amy S., Zhou, Beiyun
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2020
Schlagworte:
Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6961744/
https://ncbi.nlm.nih.gov/pubmed/31738079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201902-0451OC
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge