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Beyond the endoplasmic reticulum: atypical GRP78 in cell viability, signaling and therapeutic targeting

GRP78 is traditionally regarded as a major endoplasmic reticulum (ER) chaperone facilitating protein folding and assembly, protein quality control, Ca(2+) binding and regulating ER stress signaling. It is a potent anti-apoptotic protein and plays a critical role in tumor cell survival, tumor progres...

詳細記述

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書誌詳細
主要な著者: Ni, Min, Zhang, Yi, Lee, Amy S.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353658/
https://ncbi.nlm.nih.gov/pubmed/21309747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20101569
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