Deep proteomic analysis of Dnmt1 mutant/hypomorphic colorectal cancer cells reveals dysregulation of epithelial–mesenchymal transition and subcellular re-localization of Beta-Catenin

DNA methyltransferase I plays the central role in maintenance of CpG DNA methylation patterns across the genome and alteration of CpG methylation patterns is a frequent and significant occurrence across many cancers. Cancer cells carrying hypomorphic alleles of Dnmt1 have become important tools for...

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Detalhes bibliográficos
Publicado no:Epigenetics
Main Authors: Bowler, Emily H, Smith-Vidal, Alex, Lester, Alex, Bell, Joseph, Wang, Zhenghe, Bell, Christopher G., Wang, Yihua, Divecha, Nullin, Skipp, Paul J., Ewing, Rob M.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6961695/
https://ncbi.nlm.nih.gov/pubmed/31448663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2019.1656154
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