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A protein interaction between β-catenin and Dnmt1 regulates Wnt Signaling and DNA methylation in colorectal cancer cells

Aberrant activation of the Wnt signaling pathway is an important step in the initiation and progression of tumor development in diverse cancers. The central effector of canonical Wnt signaling, β-catenin (CTNNB1), is a multifunctional protein, and has been extensively studied with respect to its rol...

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Podrobná bibliografie
Vydáno v:Mol Cancer Res
Hlavní autoři: Song, Jing, Du, Zhanwen, Ravasz, Mate, Dong, Bohan, Wang, Zhenghe, Ewing, Rob M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4470773/
https://ncbi.nlm.nih.gov/pubmed/25753001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-13-0644
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