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Farnesoid X receptor antagonizes Wnt/β-catenin signaling in colorectal tumorigenesis
Farnesoid X receptor (FXR, encoded by NR1H4), a critical regulator of bile acid homeostasis, is widely implicated in human tumorigenesis. However, the functional role of FXR in colorectal cancer (CRC) and the precise molecular mechanism remain unclear. In this study, we demonstrated that FXR express...
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| Publicado no: | Cell Death Dis |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7431544/ https://ncbi.nlm.nih.gov/pubmed/32807788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02819-w |
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