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Farnesoid X receptor antagonizes Wnt/β-catenin signaling in colorectal tumorigenesis
Farnesoid X receptor (FXR, encoded by NR1H4), a critical regulator of bile acid homeostasis, is widely implicated in human tumorigenesis. However, the functional role of FXR in colorectal cancer (CRC) and the precise molecular mechanism remain unclear. In this study, we demonstrated that FXR express...
Gespeichert in:
| Veröffentlicht in: | Cell Death Dis |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7431544/ https://ncbi.nlm.nih.gov/pubmed/32807788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02819-w |
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