Farnesoid X receptor antagonizes Wnt/β-catenin signaling in colorectal tumorigenesis

Farnesoid X receptor (FXR, encoded by NR1H4), a critical regulator of bile acid homeostasis, is widely implicated in human tumorigenesis. However, the functional role of FXR in colorectal cancer (CRC) and the precise molecular mechanism remain unclear. In this study, we demonstrated that FXR express...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Dis
Prif Awduron: Yu, Junhui, Li, Shan, Guo, Jing, Xu, Zhengshui, Zheng, Jianbao, Sun, Xuejun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7431544/
https://ncbi.nlm.nih.gov/pubmed/32807788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02819-w
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