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Farnesoid X receptor antagonizes Wnt/β-catenin signaling in colorectal tumorigenesis
Farnesoid X receptor (FXR, encoded by NR1H4), a critical regulator of bile acid homeostasis, is widely implicated in human tumorigenesis. However, the functional role of FXR in colorectal cancer (CRC) and the precise molecular mechanism remain unclear. In this study, we demonstrated that FXR express...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Cell Death Dis |
|---|---|
| Prif Awduron: | , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Nature Publishing Group UK
2020
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7431544/ https://ncbi.nlm.nih.gov/pubmed/32807788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02819-w |
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