Wnt2 complements Wnt/β-catenin signaling in colorectal cancer

Wnt2 is implicated in various human cancers. However, it remains unknown how Wnt2 is upregulated in human cancer and contributes to tumorigenesis. Here we found that Wnt2 is highly expressed in colorectal cancer (CRC) cells. In addition to co-expression of Wnt2 with Wnt/β-catenin target genes in CRC...

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Udgivet i:Oncotarget
Main Authors: Jung, Youn-Sang, Jun, Sohee, Lee, Sun Hye, Sharma, Amrish, Park, Jae-Il
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741928/
https://ncbi.nlm.nih.gov/pubmed/26484565
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