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Wnt signaling in cancer: therapeutic targeting of Wnt signaling beyond β-catenin and the destruction complex

Wnt/β-catenin signaling is implicated in many physiological processes, including development, tissue homeostasis, and tissue regeneration. In human cancers, Wnt/β-catenin signaling is highly activated, which has led to the development of various Wnt signaling inhibitors for cancer therapies. Nonethe...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Jung, Youn-Sang, Park, Jae-Il
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7062731/
https://ncbi.nlm.nih.gov/pubmed/32037398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-020-0380-6
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