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Identification of targets of the Wnt pathway destruction complex in addition to β-catenin

The proteasomal degradation of β-catenin mediated by the glycogen synthase kinase 3β (GSK3β) and destruction complex is the central step in the canonical Wnt signaling pathway. However, that there are branches of Wnt signaling pathways that do not depend on β-catenin/Tcf-mediated transcription activ...

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Detalhes bibliográficos
Main Authors: Kim, Nam-Gyun, Xu, Chong, Gumbiner, Barry M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663984/
https://ncbi.nlm.nih.gov/pubmed/19289839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810185106
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