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Molecular regulation and pharmacological targeting of the β‐catenin destruction complex

The β‐catenin destruction complex is a dynamic cytosolic multiprotein assembly that provides a key node in Wnt signalling regulation. The core components of the destruction complex comprise the scaffold proteins axin and adenomatous polyposis coli and the Ser/Thr kinases casein kinase 1 and glycogen...

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Dades bibliogràfiques
Publicat a:Br J Pharmacol
Autors principals: van Kappel, Eline C, Maurice, Madelon M
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727331/
https://ncbi.nlm.nih.gov/pubmed/28634996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13922
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