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Quiescence Exit of Tert+ Stem Cells by Wnt/β-Catenin Is Indispensable for Intestinal Regeneration
Fine control of stem cell maintenance and activation is crucial for tissue homeostasis and regeneration. However, the mechanism of quiescence exit of Tert+ intestinal stem cells (ISCs) remains unknown. Employing a Tert knock-in (Tert(TCE/+)) mouse model, we found that Tert+ cells are long-term label...
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| Veröffentlicht in: | Cell Rep |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5726811/ https://ncbi.nlm.nih.gov/pubmed/29186692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.10.118 |
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