FOXKs promote Wnt/β-catenin signaling by translocating DVL into the nucleus

Dishevelled (DVL) proteins serve as crucial regulators that transduce canonical Wnt signals to the GSK3β-destruction complex, resulting in the stabilization of β-catenin. Emerging evidences underscore the nuclear functions of DVLs, which are critical for the Wnt/β-catenin signaling. However, the mec...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Wang, Wenqi, Li, Xu, Lee, Moonsup, Jun, Sohee, Aziz, Kathryn E., Feng, Lin, Tran, My Kim, Li, Nan, McCrea, Pierre D., Park, Jae-Il, Chen, Junjie
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374128/
https://ncbi.nlm.nih.gov/pubmed/25805136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2015.01.031
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