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Dvl3 Translocates IPMK to the cell membrane in response to Wnt
Wnt3a binds Frizzled-1 and the LRP5/6 co-receptors, ultimately activating Lef/Tcf-sensitive gene transcription in development. Inositol polyphosphate multikinase, IPMK, possesses inositol phosphate kinase and lipid inositol kinase activities, is essential in Wnt3a regulation of its canonical pathway...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3482508/ https://ncbi.nlm.nih.gov/pubmed/22940627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2012.08.009 |
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