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Signalling activity of beta-catenin targeted to different subcellular compartments.

Beta-catenin plays a dual role as an adhesion molecule in adherens junctions at the plasma membrane and as a key intermediate in the canonical Wnt signalling pathway. The cytosolic soluble pool of beta-catenin, involved in the transmission of the Wnt signal, is normally subjected to rapid protein de...

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Autors principals: Hagen, Thilo, Sethi, Jaswinder K, Foxwell, Neale, Vidal-Puig, Antonio
Format: Artigo
Idioma:Inglês
Publicat: 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224088/
https://ncbi.nlm.nih.gov/pubmed/14733614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031749
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