Reduction of pancreatic acinar cell tumor multiplicity in Dnmt1 hypomorphic mice

In human pancreatic cancers, promoter CpG island hypermethylation is observed in both benign and malignant tumors. It is thought that silencing of key growth-controlling genes by promoter hypermethylation may play a role in pancreatic oncogenesis. We have shown previously that sufficient levels of D...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Oghamian, Shirley, Sodir, Nicole M., Bashir, Muhammad U., Shen, Hui, Cullins, Andrea E., Carroll, Cindy A., Kundu, Pratima, Shibata, Darryl, Laird, Peter W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2011
Pynciau:
Cancer Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3106433/
https://ncbi.nlm.nih.gov/pubmed/21362628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgr039
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