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Reduction of pancreatic acinar cell tumor multiplicity in Dnmt1 hypomorphic mice

In human pancreatic cancers, promoter CpG island hypermethylation is observed in both benign and malignant tumors. It is thought that silencing of key growth-controlling genes by promoter hypermethylation may play a role in pancreatic oncogenesis. We have shown previously that sufficient levels of D...

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Detalles Bibliográficos
Main Authors: Oghamian, Shirley, Sodir, Nicole M., Bashir, Muhammad U., Shen, Hui, Cullins, Andrea E., Carroll, Cindy A., Kundu, Pratima, Shibata, Darryl, Laird, Peter W.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3106433/
https://ncbi.nlm.nih.gov/pubmed/21362628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgr039
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