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Targeting the orphan nuclear receptor NR2F6 in T cells primes tumors for immune checkpoint therapy
BACKGROUND: NR2F6 has been proposed as an alternative cancer immune checkpoint in the effector T cell compartment. However, a realistic assessment of the in vivo therapeutic potential of NR2F6 requires acute depletion. METHODS: Employing primary T cells isolated from Cas9-transgenic mice for electro...
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| Publicado no: | Cell Commun Signal |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6961368/ https://ncbi.nlm.nih.gov/pubmed/31937317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-019-0454-z |
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