Loss of the orphan nuclear receptor NR2F6 enhances CD8(+) T-cell memory via IFN-γ

Memory formation is a hallmark of T cell-mediated immunity, but how differentiation into either short-lived effector cells (SLECs, CD127(−)KLRG1(+)) or memory precursors cells (MPECs, CD127(+)KLRG1(−)) and subsequent regulation of long-term memory is adjusted is incompletely understood. Here, we sho...

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Bibliografske podrobnosti
izdano v:Cell Death Dis
Main Authors: Jakic, Bojana, Olson, William J., Siegmund, Kerstin, Klepsch, Victoria, Kimpel, Janine, Labi, Verena, Zehn, Dietmar, Baier, Gottfried, Hermann-Kleiter, Natascha
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7884426/
https://ncbi.nlm.nih.gov/pubmed/33589606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03470-9
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