FGF14 Functions as a Tumor Suppressor through Inhibiting PI3K/AKT/mTOR Pathway in Colorectal Cancer

We identified that Fibroblast Growth Factor 14 (FGF14) was preferentially methylated in colorectal cancer (CRC). In this study, we aimed to investigate the epigenetic regulation, biological function and molecular mechanism of FGF14 in CRC. The expression of FGF14 in CRC cell lines, normal human colo...

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Bibliografiske detaljer
Udgivet i:J Cancer
Main Authors: Su, Tianhong, Huang, Linlin, Zhang, Ning, Peng, Sui, Li, Xiaoxing, Wei, Guangyan, Zhai, Ertao, Zeng, Zhirong, Xu, Lixia
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2020
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959027/
https://ncbi.nlm.nih.gov/pubmed/31949485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.36316
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