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FGF14 Functions as a Tumor Suppressor through Inhibiting PI3K/AKT/mTOR Pathway in Colorectal Cancer

We identified that Fibroblast Growth Factor 14 (FGF14) was preferentially methylated in colorectal cancer (CRC). In this study, we aimed to investigate the epigenetic regulation, biological function and molecular mechanism of FGF14 in CRC. The expression of FGF14 in CRC cell lines, normal human colo...

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Detalhes bibliográficos
Publicado no:J Cancer
Main Authors: Su, Tianhong, Huang, Linlin, Zhang, Ning, Peng, Sui, Li, Xiaoxing, Wei, Guangyan, Zhai, Ertao, Zeng, Zhirong, Xu, Lixia
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959027/
https://ncbi.nlm.nih.gov/pubmed/31949485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.36316
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