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Hypoxia-inducible factor (HIF)-1alpha knockout accelerates intervertebral disc degeneration in mice

Introduction: The abnormality of nucleus pulposus (NP) plays a critical role in intervertebral disc (IVD) degeneration, in which NP cells show apoptosis and fibrosis, leading to the ability of the disc to transfer and distribute loads between the vertebrae is decreased. Considering that hypoxia indu...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Int J Clin Exp Pathol
Päätekijät: Meng, Xiangchao, Zhuang, Lingling, Wang, Jun, Liu, Zhuochao, Wang, You, Xiao, Dechang, Zhang, Xingkai
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: e-Century Publishing Corporation 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6957989/
https://ncbi.nlm.nih.gov/pubmed/31938140
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