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Progranulin Knockout Accelerates Intervertebral Disc Degeneration in Aging Mice
Intervertebral disc (IVD) degeneration is a common degenerative disease, yet much is unknown about the mechanisms during its pathogenesis. Herein we investigated whether progranulin (PGRN), a chondroprotective growth factor, is associated with IVD degeneration. PGRN was detectable in both human and...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4894449/ https://ncbi.nlm.nih.gov/pubmed/25777988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09102 |
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