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Accelerated cellular senescence in degenerate intervertebral discs: a possible role in the pathogenesis of intervertebral disc degeneration

Current evidence implicates intervertebral disc degeneration as a major cause of low back pain, although its pathogenesis is poorly understood. Numerous characteristic features of disc degeneration mimic those seen during ageing but appear to occur at an accelerated rate. We hypothesised that this i...

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Detalhes bibliográficos
Main Authors: Le Maitre, Christine Lyn, Freemont, Anthony John, Hoyland, Judith Alison
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2206356/
https://ncbi.nlm.nih.gov/pubmed/17498290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2198
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