The role of interleukin-1 in the pathogenesis of human Intervertebral disc degeneration

In this study, we investigated the hypotheses that in human intervertebral disc (IVD) degeneration there is local production of the cytokine IL-1, and that this locally produced cytokine can induce the cellular and matrix changes of IVD degeneration. Immunohistochemistry was used to localize five me...

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Bibliographic Details
Main Authors: Le Maitre, Christine Lyn, Freemont, Anthony J, Hoyland, Judith Alison
Format: Artigo
Language:Inglês
Published: BioMed Central 2005
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1175026/
https://ncbi.nlm.nih.gov/pubmed/15987475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1732
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