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Progranulin protects against osteoarthritis through interacting with TNF-α and β-Catenin signalling
OBJECTIVE: Progranulin (PGRN) was previously isolated as an osteoarthritis (OA)-associated growth factor. Additionally, PGRN was found to play a therapeutic role in inflammatory arthritis mice models through antagonising tumour necrosis factor α (TNF-α). This study was aimed at investigating the rol...
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| Publicado no: | Ann Rheum Dis |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4408266/ https://ncbi.nlm.nih.gov/pubmed/25169730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2014-205779 |
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