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Progranulin protects against osteoarthritis through interacting with TNF-α and β-Catenin signalling

OBJECTIVE: Progranulin (PGRN) was previously isolated as an osteoarthritis (OA)-associated growth factor. Additionally, PGRN was found to play a therapeutic role in inflammatory arthritis mice models through antagonising tumour necrosis factor α (TNF-α). This study was aimed at investigating the rol...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Ann Rheum Dis
Main Authors: Zhao, Yun-peng, Liu, Ben, Tian, Qing-yun, Wei, Jian-lu, Richbourgh, Brendon, Liu, Chuan-ju
פורמט: Artigo
שפה:Inglês
יצא לאור: 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408266/
https://ncbi.nlm.nih.gov/pubmed/25169730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2014-205779
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