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NORE1A Tumor Suppressor Candidate Modulates p21(CIP1) via p53

NORE1A (RASSF5) is a proapoptotic Ras effector that is frequently inactivated by promoter methylation in human tumors. It is structurally related to the RASSF1A tumor suppressor and is itself implicated as a tumor suppressor. In the presence of activated Ras, NORE1A is a potent inducer of apoptosis....

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Detalles Bibliográficos
Publicado en:Cancer Res
Main Authors: Calvisi, Diego F., Donninger, Howard, Vos, Michele D., Birrer, Michael J., Gordon, Laura, Leaner, Virna, Clark, Geoffrey J.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6957251/
https://ncbi.nlm.nih.gov/pubmed/19435914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3672
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