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The Role of the NORE1A Tumor Suppressor in Oncogene-Induced Senescence

The Ras genes are the most frequently mutated oncogenes in human cancer. However, Ras biology is quite complex. While Ras promotes tumorigenesis by regulating numerous growth promoting pathways, activated Ras can paradoxically also lead to cell cycle arrest, death, and Oncogene-Induced Senescence (O...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancer Lett
Prif Awduron: Barnoud, Thibaut, Schmidt, M. Lee, Donninger, Howard, Clark, Geoffrey J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502528/
https://ncbi.nlm.nih.gov/pubmed/28455242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2017.04.030
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