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The Role of the NORE1A Tumor Suppressor in Oncogene-Induced Senescence
The Ras genes are the most frequently mutated oncogenes in human cancer. However, Ras biology is quite complex. While Ras promotes tumorigenesis by regulating numerous growth promoting pathways, activated Ras can paradoxically also lead to cell cycle arrest, death, and Oncogene-Induced Senescence (O...
Gardado en:
| Publicado en: | Cancer Lett |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5502528/ https://ncbi.nlm.nih.gov/pubmed/28455242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2017.04.030 |
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