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NORE1A is a Ras senescence effector that controls the apoptotic/senescent balance of p53 via HIPK2
The Ras oncoprotein is a key driver of cancer. However, Ras also provokes senescence, which serves as a major barrier to Ras-driven transformation. Ras senescence pathways remain poorly characterized. NORE1A is a novel Ras effector that serves as a tumor suppressor. It is frequently inactivated in t...
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| Publicado no: | J Cell Biol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4362463/ https://ncbi.nlm.nih.gov/pubmed/25778922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201408087 |
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