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Nore1a drives Ras to flick the P53 senescence switch
RAS-induced senescence is a protective mechanism to avoid unrestricted cell growth due to aberrant mitogenic signals; however, the exact mechanism by which RAS induces senescence is not known. We recently identified a novel pathway linking RAS to p53 via NORE1A and HIPK2 that mechanistically explain...
Gorde:
| Argitaratua izan da: | Mol Cell Oncol |
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| Egile Nagusiak: | , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Taylor & Francis
2015
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4909421/ https://ncbi.nlm.nih.gov/pubmed/27314075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1055050 |
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