Differential Expression of Immune Checkpoint Molecules on CD8(+) T Cells Specific for Immunodominant and Subdominant Herpes Simplex Virus 1 Epitopes

Herpes simplex virus 1 (HSV-1) causes a lifelong infection of neurons that innervate barrier sites like the skin and mucosal surfaces like the eye. After primary infection of the cornea, the virus enters latency within the trigeminal ganglion (TG), from which it can reactivate throughout the life of...

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Udgivet i:J Virol
Main Authors: Carroll, Kate L., Avery, Lyndsay, Treat, Benjamin R., Kane, Lawrence P., Kinchington, Paul R., Hendricks, Robert L., St. Leger, Anthony J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2020
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6955272/
https://ncbi.nlm.nih.gov/pubmed/31645447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01132-19
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