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Reevaluating the CD8 T-Cell Response to Herpes Simplex Virus Type 1: Involvement of CD8 T Cells Reactive to Subdominant Epitopes

In C57BL/6 (B6) mice, most herpes simplex virus (HSV)-specific CD8 T cells recognize a strongly immunodominant epitope on glycoprotein B (gB(498)) and can inhibit HSV type 1 (HSV-1) reactivation from latency in trigeminal ganglia (TG). However, half of the CD8 T cells retained in latently infected T...

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Detalhes bibliográficos
Main Authors: Sheridan, Brian S., Cherpes, Thomas L., Urban, Julie, Kalinski, Pawel, Hendricks, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643732/
https://ncbi.nlm.nih.gov/pubmed/19073721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01699-08
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