Beyond the heterodimer model for mineralocorticoid and glucocorticoid receptor interactions in nuclei and at DNA

Glucocorticoid (GR) and mineralocorticoid receptors (MR) are believed to classically bind DNA as homodimers or MR-GR heterodimers to influence gene regulation in response to pulsatile basal or stress-evoked glucocorticoid secretion. Pulsed corticosterone presentation reveals MR and GR co-occupy DNA...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Pooley, John R., Rivers, Caroline A., Kilcooley, Michael T., Paul, Susana N., Cavga, Ayse Derya, Kershaw, Yvonne M., Muratcioglu, Serena, Gursoy, Attila, Keskin, Ozlem, Lightman, Stafford L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6953809/
https://ncbi.nlm.nih.gov/pubmed/31923266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0227520
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