Beyond the heterodimer model for mineralocorticoid and glucocorticoid receptor interactions in nuclei and at DNA

Glucocorticoid (GR) and mineralocorticoid receptors (MR) are believed to classically bind DNA as homodimers or MR-GR heterodimers to influence gene regulation in response to pulsatile basal or stress-evoked glucocorticoid secretion. Pulsed corticosterone presentation reveals MR and GR co-occupy DNA...

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Vydáno v:PLoS One
Hlavní autoři: Pooley, John R., Rivers, Caroline A., Kilcooley, Michael T., Paul, Susana N., Cavga, Ayse Derya, Kershaw, Yvonne M., Muratcioglu, Serena, Gursoy, Attila, Keskin, Ozlem, Lightman, Stafford L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6953809/
https://ncbi.nlm.nih.gov/pubmed/31923266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0227520
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