Beyond the heterodimer model for mineralocorticoid and glucocorticoid receptor interactions in nuclei and at DNA

Glucocorticoid (GR) and mineralocorticoid receptors (MR) are believed to classically bind DNA as homodimers or MR-GR heterodimers to influence gene regulation in response to pulsatile basal or stress-evoked glucocorticoid secretion. Pulsed corticosterone presentation reveals MR and GR co-occupy DNA...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Pooley, John R., Rivers, Caroline A., Kilcooley, Michael T., Paul, Susana N., Cavga, Ayse Derya, Kershaw, Yvonne M., Muratcioglu, Serena, Gursoy, Attila, Keskin, Ozlem, Lightman, Stafford L.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2020
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6953809/
https://ncbi.nlm.nih.gov/pubmed/31923266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0227520
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