Primary cilia signaling promotes axonal tract development and is disrupted in Joubert Syndrome Related Disorder models

Appropriate axonal growth and connectivity are essential for functional wiring of the brain. Joubert Syndrome Related disorders (JSRD), a group of ciliopathies in which mutations disrupt primary cilia function, are characterized by axonal tract malformations. However, little is known about how cilia...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Guo, Jiami, Otis, James, Suciu, Sarah K., Catalano, Christy, Xing, Lei, Constable, Sandii, Wachten, Dagmar, Gupton, Stephanie, Lee, Janice, Lee, Amelia, Blackley, Katherine H., Ptacek, Travis, Simon, Jeremy M., Schurmans, Stephane, Stuber, Garret D., Caspary, Tamara, Anton, E. S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6953258/
https://ncbi.nlm.nih.gov/pubmed/31846650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2019.11.005
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