The ciliary phosphatidylinositol phosphatase Inpp5e plays positive and negative regulatory roles in Shh signaling

Sonic hedgehog (Shh) signal transduction specifies ventral cell fates in the neural tube and is mediated by the Gli transcription factors that play both activator (GliA) and repressor (GliR) roles. Cilia are essential for Shh signal transduction and the ciliary phosphatidylinositol phosphatase Inpp5...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Constable, Sandii, Long, Alyssa B., Floyd, Katharine A., Schurmans, Stéphane, Caspary, Tamara
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7033722/
https://ncbi.nlm.nih.gov/pubmed/31964774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.183301
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