Primary cilia signaling promotes axonal tract development and is disrupted in Joubert Syndrome Related Disorder models

Appropriate axonal growth and connectivity are essential for functional wiring of the brain. Joubert Syndrome Related disorders (JSRD), a group of ciliopathies in which mutations disrupt primary cilia function, are characterized by axonal tract malformations. However, little is known about how cilia...

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Publicat a:Dev Cell
Autors principals: Guo, Jiami, Otis, James, Suciu, Sarah K., Catalano, Christy, Xing, Lei, Constable, Sandii, Wachten, Dagmar, Gupton, Stephanie, Lee, Janice, Lee, Amelia, Blackley, Katherine H., Ptacek, Travis, Simon, Jeremy M., Schurmans, Stephane, Stuber, Garret D., Caspary, Tamara, Anton, E. S.
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6953258/
https://ncbi.nlm.nih.gov/pubmed/31846650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2019.11.005
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