Quantitative assessment of CMTM6 in the tumor microenvironment and association with response to PD-1 pathway blockade in advanced-stage non-small-cell lung cancer

INTRODUCTION: CMTM6 has been described as a PD-L1 regulator at the protein level by modulating stability via ubiquitination. In this study, we describe the patterns of CMTM6 expression and assess its association with response to PD-1 pathway blockade in non-small-cell lung cancer (NSCLC). METHODS: W...

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Publicado en:J Thorac Oncol
Autores principales: Zugazagoitia, Jon, Liu, Yuting, Toki, Maria, McGuire, John, Ahmed, Fahad Shabbir, Henick, Brian S., Gupta, Richa, Gettinger, Scott, Herbst, Roy, Schalper, Kurt A., Rimm, David L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6951804/
https://ncbi.nlm.nih.gov/pubmed/31605795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtho.2019.09.014
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