Quantitative analysis of CMTM6 expression in tumor microenvironment in metastatic melanoma and association with outcome on immunotherapy

Chemokine-like factor (CKLF)-like MARVEL transmembrane domain containing 6 (CMTM6) modulates degradation of a number of proteins, including programmed death ligand-1 (PD-L1) by protecting it from ubiquitin-mediated degradation. In this role, it could modulate the effectiveness of immunotherapy. Here...

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Опубликовано в: :Oncoimmunology
Главные авторы: Martinez-Morilla, Sandra, Zugazagoitia, Jon, Wong, Pok Fai, Kluger, Harriet M., Rimm, David L.
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 2020
Предметы:
Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7781756/
https://ncbi.nlm.nih.gov/pubmed/33457084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2020.1864909
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