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Multiplex quantitative analysis of tumor-infiltrating lymphocytes and immunotherapy outcome in metastatic melanoma

PURPOSE: Since durable response to programmed cell death 1 (PD-1) inhibition is limited to a subset of melanoma patients, new predictive biomarkers could have clinical utility. We hypothesize that pretreatment tumor-infiltrating lymphocyte (TIL) profiles could be associated with response. METHODS: P...

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Vydáno v:Clin Cancer Res
Hlavní autoři: Wong, Pok Fai, Wei, Wei, Smithy, James W., Acs, Balazs, Toki, Maria I., Blenman, Kim R.M., Zelterman, Daniel, Kluger, Harriet M., Rimm, David L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467753/
https://ncbi.nlm.nih.gov/pubmed/30617133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-2652
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