Multiplex quantitative analysis of cancer-associated fibroblasts and immunotherapy outcome in metastatic melanoma

BACKGROUND: The cancer-associated fibroblast (CAF) population is implicated in immune dysregulation. Here, we test the hypothesis that CAF profiles in pretreatment tumor specimens are associated with response to immune checkpoint blockade of programmed cell death 1 (PD-1). METHODS: Pretreatment whol...

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Detaylı Bibliyografya
Yayımlandı:J Immunother Cancer
Asıl Yazarlar: Wong, Pok Fai, Wei, Wei, Gupta, Swati, Smithy, James W., Zelterman, Daniel, Kluger, Harriet M., Rimm, David L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2019
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6651990/
https://ncbi.nlm.nih.gov/pubmed/31337426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-019-0675-0
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