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B7-H3 expression in NSCLC and its association with B7-H4, PD-L1 and Tumor Infiltrating Lymphocytes

BACKGROUND AND PURPOSE: The immune checkpoint PD-1 and its receptor B7-H1 (PD-L1) are successful therapeutic targets in cancer but less is known about other B7 family members. Here, we determined the expression level of B7-H3 protein in non-small cell lung cancer (NSCLC) and evaluated its associatio...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Altan, Mehmet, Pelekanou, Vasiliki, Schalper, Kurt A., Toki, Maria, Gaule, Patricia, Syrigos, Konstantinos, Herbst, Roy S., Rimm, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581684/
https://ncbi.nlm.nih.gov/pubmed/28539467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-3107
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